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Current Oncology | Free Full-Text | Precision Oncology in Gastrointestinal  Stromal Tumors
Current Oncology | Free Full-Text | Precision Oncology in Gastrointestinal Stromal Tumors

A new monoclonal antibody that blocks dimerisation and inhibits c-kit  mutation-driven tumour growth | Journal of Cancer Research and Clinical  Oncology
A new monoclonal antibody that blocks dimerisation and inhibits c-kit mutation-driven tumour growth | Journal of Cancer Research and Clinical Oncology

Computational Analysis of the Binding Specificity of Gleevec to Abl, c-Kit,  Lck, and c-Src Tyrosine Kinases | Journal of the American Chemical Society
Computational Analysis of the Binding Specificity of Gleevec to Abl, c-Kit, Lck, and c-Src Tyrosine Kinases | Journal of the American Chemical Society

Diapositiva 1
Diapositiva 1

Reactome | Drug resistance of KIT mutants
Reactome | Drug resistance of KIT mutants

Cancer drug gets a makeover | News | Chemistry World
Cancer drug gets a makeover | News | Chemistry World

Loss of PI3 kinase association improves the sensitivity of secondary  mutation of KIT to Imatinib | Cell & Bioscience | Full Text
Loss of PI3 kinase association improves the sensitivity of secondary mutation of KIT to Imatinib | Cell & Bioscience | Full Text

Imatinib Mesylate — A New Oral Targeted Therapy | NEJM
Imatinib Mesylate — A New Oral Targeted Therapy | NEJM

Presentazione standard di PowerPoint
Presentazione standard di PowerPoint

Frontiers | An overview of agents and treatments for PDGFRA-mutated  gastrointestinal stromal tumors
Frontiers | An overview of agents and treatments for PDGFRA-mutated gastrointestinal stromal tumors

Secondary KIT mutations: the GIST of drug resistance and sensitivity |  British Journal of Cancer
Secondary KIT mutations: the GIST of drug resistance and sensitivity | British Journal of Cancer

Complementary activity of tyrosine kinase inhibitors against secondary kit  mutations in imatinib-resistant gastrointestinal stromal tumours | British  Journal of Cancer
Complementary activity of tyrosine kinase inhibitors against secondary kit mutations in imatinib-resistant gastrointestinal stromal tumours | British Journal of Cancer

Acquired resistance to imatinib in gastrointestinal stromal tumours caused  by multiple KIT mutations - The Lancet Oncology
Acquired resistance to imatinib in gastrointestinal stromal tumours caused by multiple KIT mutations - The Lancet Oncology

Frontiers | Early and Next-Generation KIT/PDGFRA Kinase Inhibitors and the  Future of Treatment for Advanced Gastrointestinal Stromal Tumor
Frontiers | Early and Next-Generation KIT/PDGFRA Kinase Inhibitors and the Future of Treatment for Advanced Gastrointestinal Stromal Tumor

The KIT receptor tyrosine kinase. (A) C-KIT mutations occur in 80 –90%... |  Download Scientific Diagram
The KIT receptor tyrosine kinase. (A) C-KIT mutations occur in 80 –90%... | Download Scientific Diagram

Ripretinib in advanced gastrointestinal stromal tumors: an overview of  current evidence and drug approval | Future Oncology
Ripretinib in advanced gastrointestinal stromal tumors: an overview of current evidence and drug approval | Future Oncology

A novel anti‐c‐Kit antibody–drug conjugate to treat wild‐type and  activating‐mutant c‐Kit‐positive tumors - Kim - 2022 - Molecular Oncology -  Wiley Online Library
A novel anti‐c‐Kit antibody–drug conjugate to treat wild‐type and activating‐mutant c‐Kit‐positive tumors - Kim - 2022 - Molecular Oncology - Wiley Online Library

PDF] The SCF/c-KIT system and imatinib actions in prostate cancer: a  cross-talk with RGN? | Semantic Scholar
PDF] The SCF/c-KIT system and imatinib actions in prostate cancer: a cross-talk with RGN? | Semantic Scholar

Mechanisms of Disease Persistence in Gastrointestinal Stromal Tumors - The  Life Raft Group
Mechanisms of Disease Persistence in Gastrointestinal Stromal Tumors - The Life Raft Group

Mechanism of action of imatinib. A) Under physiological conditions, ATP...  | Download Scientific Diagram
Mechanism of action of imatinib. A) Under physiological conditions, ATP... | Download Scientific Diagram

Clinicopathological significance of c-KIT mutation in gastrointestinal  stromal tumors: a systematic review and meta-analysis | Scientific Reports
Clinicopathological significance of c-KIT mutation in gastrointestinal stromal tumors: a systematic review and meta-analysis | Scientific Reports

Frontiers | Systemic Mastocytosis: Following the Tyrosine Kinase Inhibition  Roadmap
Frontiers | Systemic Mastocytosis: Following the Tyrosine Kinase Inhibition Roadmap

GIST Mutations - Types of GIST Cancer Gene Mutations & Testing | The Life  Raft Group
GIST Mutations - Types of GIST Cancer Gene Mutations & Testing | The Life Raft Group

KIT mutation | The Hong Kong College of Pathologists
KIT mutation | The Hong Kong College of Pathologists

IJMS | Free Full-Text | Mutated KIT Tyrosine Kinase as a Novel Molecular  Target in Acute Myeloid Leukemia
IJMS | Free Full-Text | Mutated KIT Tyrosine Kinase as a Novel Molecular Target in Acute Myeloid Leukemia

JCI - Structural reengineering of imatinib to decrease cardiac risk in  cancer therapy
JCI - Structural reengineering of imatinib to decrease cardiac risk in cancer therapy

Visualisation of the action of imatinib at the KIT receptor | Download  Scientific Diagram
Visualisation of the action of imatinib at the KIT receptor | Download Scientific Diagram